MOTS-C

MOTS-C is an investigational research peptide derived from mitochondrial DNA and classified as a mitochondrial-encoded regulatory peptide. It has gained significant interest for its role in cellular metabolism, stress-response pathways, and energy homeostasis. Preclinical studies suggest that MOTS-C may influence AMPK signalling, metabolic flexibility, and cellular adaptation under conditions of metabolic stress, making it a valuable tool for researchers studying metabolic regulation.

Preclinical and in vitro research has indicated that MOTS-C may offer potential in the following areas:

Supporting investigations into AMPK activation and energy-regulating pathways.

Examining metabolic resilience during cellular stress or nutrient fluctuations.

Exploring glucose utilisation and insulin sensitivity in metabolic models.

Assessing mitochondrial function and adaptive cellular signalling.

Studying potential protective effects in oxidative or inflammatory environments.